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viagra (sildenafil)

Viagra is the most popular drug for erection recovery

viagra (sildenafil)

Viagra is the most popular drug for erection recovery

As it is known, this medicine was initially developed to help patients with angina and its purpose was to improve blood circulation. Viagra was supposed to help in the treatment of coronary heart disease. But tests showed that the drug has little effect to the blood flow in the heart, but works perfectly in the pelvic area, in particular, improving the blood flow in the penis.

Since then pills with the active ingredient sildenafil under the commercial name Viagra have been used for erectile dysfunction (ED) treatment. They help to achieve sustainable and prolonged erection. The drug does not evoke the spontaneous erection, the sexual arousal is required for it.

Why do the erection problems occur?

The circulation in the pelvic organs can be disrupted for a number of reasons: medications administration, diseases, including, colds, and injuries. Natural flow may be insufficient and full erection does not occur. This requires timely treatment. Such drugs as Viagra are used for such cases.

Indications for use

Viagra is prescribed at the disorders of erectile function, including of psychological character. By the way, namely mental disorders and neurosis often cannot be completely treated.

Pharmacokinetics

Sexual arousal of healthy men has certain consequences – the normal response is accompanied by an erection. But physiology is such that blood flow is possible only at the release of nitric oxide, i.e. it activates the enzyme Guanylate cyclase, the smooth muscles of the penis relaxes, blood flow increases. The active component of Viagra sildenafil inhibits PDE-5, blocking it and relaxing the muscles. The patient should be sexually excited in order to activate its action.

Sildenafil is rapidly absorbed and inhibits the action of phosphodiesterase-5 at 50%. The efficiency is achieved approximately in 30 - 60 minutes when taken on an empty stomach. The fatty food decreases the speed of drug absorption. Sildenafil bounds to plasma proteins at about 96%. The amount of the dose of Viagra that gets in sperm after the tablet administration can be disregarded statistically.

The drug is excreted mainly with faeces (80%) and the rest with urine. The clearance rate of sildenafil in older healthy people will be reduced. Side effects do not depend on age. Mild and moderate renal failure is not contraindications for Viagra taking. At severe failure the concentration of sildenafil is doubled compared to healthy people. The same applies to those who suffer from liver cirrhosis.

Viagra 25 mg

A solution to the problem of male impotence - the drug Sildenafil 25 mg. This medication is especially effective, as evidenced by the positive reviews of patients. The main difference of this medication is the possibility for use by older people. Without harming health, the remedy at a dosage of 25 mg will provide an excellent erection to an elderly person. Sildenafil Citrate, which belongs to the pharmacotherapeutic group of selective inhibitors, is the main active ingredient in the drug. Under the impact of this substance, nitric oxide is released, as a result of which the process of erection appearance begins. The smooth muscle tissue of the penis relaxes, and the veins fill with blood.

Viagra 50 mg

Sildenafil 50 mg is an effective pharmacological drug that is used to restore and maintain erection sufficient for a normal sexual life. This effect is due to the ability of the drug to influence the enzymes responsible for the occurrence and preservation of the erect state. A positive result from the use of the drug will be observed only in the case when a man experiences natural sexual arousal. The active substance Sildenafil causes reactions in the body that contribute to the penis being filled with blood, which as a result of this process becomes hard and increases in size. Thus, there is a firm natural erection, sufficient to conduct full sexual intercourse.

Viagra 100 mg

Sildenafil is a popular medicine that is effectively used in the treatment of male sexual dysfunction. The active ingredient of the drug is Sildenafil, which contributes to the achievement of erection and supports it during the entire sexual intercourse. The widespread use of the drug is due to the fact that it is able to cope with any, even very severe, form of erectile dysfunction. A positive result from the medication is observed in men who suffer from diabetes, have a history of spinal injury or surgery on the prostate gland.

Viagra 150 mg

Clinical studies prove the positive effect of Sildenafil 150 mg on male potency and its ability to provide for an erection sufficient for a normal sexual life. However, due to the advertised brand and patent cost, the price of the drug in pharmacies is quite high. An alternative option may be a use of a similar drug with an identical chemical composition, which passed all medical research - Generic Sildenafil 150 mg.

Viagra 200 mg

To begin with, the main active ingredient is Sildenafil in the amount of 200 mg, which is indicated for men with severe erectile dysfunction, since small doses do not help them. Such a high dose has its advantages: you can save a considerable amount of money, and the effect will only increase! Such a high demand for this medicine is due to the fact that it acts in a natural way, without disrupting the activities of other important body systems.

Viagra professional

The main component of Viagra Pro is sildenafil, which, not being a hormone, affects only the humoral functions of the body. The remedy has impact only on a specific part of the body - the penis, by creating an increased blood flow. Why are side effects excluded? The substance Sildenafil contained in the medication does not have any effect on other organs than the sex organs. This feature is typical for drugs used to treat people suffering from erectile dysfunction. Only men who have reached an adult age and who are treating erectile dysfunction can take the medication.

Viagra soft

Viagra Soft is a proven drug designed to enhance the erectile function in men. Unlike analogs, the drug is sold in a form of a tablet that is easily dissolvable, which greatly accelerates the onset of the drug action due to accelerated resorption. The effect occurs within 15-20 minutes, while the generics starts to work only thirty to forty minutes later. The action of the drug is accompanied by strong erection along with increased sensations in the genital area.

Viagra super active

Sildenafil Super Active is not a classic generic that fully replicates the chemical composition of the original. In addition to the main active ingredient, the drug combines a complex of herbal extracts that have a similar effect on the human body. This makes it possible to obtain the desired therapeutic effect, while significantly reducing the risk of adverse reactions.

How to use Viagra?

Its dosage is calculated individually. Maximum single dose per day is 100 mg. The drug is available in the dose of 50 and 100 mg, optimal scheme may be chosen. The recommended dose for healthy adult is 50 mg once.

The algorithm of Viagra use:

Take 1 tablet on an empty stomach about an hour before sexual intercourse. After about 30 minutes (in some cases later) the blood will flow to the pelvic and under the condition of sexual arousal the patient reach an erection, which will allow to make sex.

Please note that the tablet should not be taken with fatty meal - the medicine will slow its action.

You should consult a doctor and to set the required dosage before use. This is important because the drug may have a negative impact at huge stress at the cardiovascular system during intercourse

  • The preliminary consultation with a doctor is needed before the dose increase
  • the drug taking only once a day
  • advanced age, renal and hepatic failure are the indications for the lowest possible dose of 25 mg.
  • in the case of some medications, the doctor will limit the dosage drug

If there are no additional risk factors the recommended dosage of Viagra does not change for the elderly.

Possible adverse effects

Viagra is usually well tolerated. In some cases, the following disorders were registered: dizziness, hypertonia, insomnia, flush of blood to the face, facial swelling, muscle pain and in abdomen, nausea, rash, temporary impairment of vision, rhinitis. However, such side effects have not been registered frequent or rare – less than 10% of cases and less than 1%. Priapism and prolonged erection were registered even more rarely.

Contraindications for use

  • sensitivity to sildenafil, lactose and other components of the tablet
  • anatomical curvature and deformation of the penis
  • severe renal and liver failure
  • ischemic stroke and myocardial infarction in the last six months
  • women and the age under 18 years
  • contraindications to have sex because of the problems of the cardiovascular system
  • taking medicines that contain nitrates and NO donors
  • heart disease
  • leukemia, myeloma and other diseases associated with impaired blood flow

Drug safety

Sildenafil has no negative impact on the quality and motility of sperm. Coadministration of sildenafil and organic nitrates can be dangerous to life. In case of overdose, side effects may appear or increase.